The best Side of ceesdekker
The best Side of ceesdekker
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2009, discovery of a brand new phenotype for microbes in narrow nanofluidic slits; and initial detection of nearby protein structures together DNA working with good-point out nanopores
Our group experiments bacterial mobile division and is also aiming to constitute a ‘base up biology’ in artificial cells that will autonomously divide. Our primary interest lies in mobile division, chromatin construction, and spatial Manage.
Back again in 1991, Sumio Iijima on the NEC Company experienced described the synthesis of carbon nanotubes. Band framework calculations instructed that these nanotubes could show metallic band conduction. This may be a big edge about the conducting polymers we experienced explored, which ended up, in truth, disordered semiconductors presenting just variable-array hopping conductivity.
Due to the fact 2000, Dekker has shifted the primary concentration of his work in direction of biophysics where by he research the Houses of one biomolecules and cells utilizing the resources of nanotechnology. This variation of industry was pushed by his fascination for your impressive performing of Organic molecular structures, and also via the long-term viewpoint that lots of appealing discoveries is usually expected Within this discipline.[5] Recent traces of exploration in his biophysics team are during the areas of:[six]
This yielded a breakthrough. In only a few months, we ended up capable to measure transport through someone single-walled carbon nanotube. Determined by reduced-temperature experiments by an excellent PhD student in my group, Sander Tans (now a valued colleague and professor at Delft College of Engineering having an Energetic investigate lab at AMOLF in Amsterdam), we showed that carbon nanotubes ended up genuine quantum wires with quite long (micrometres) electronic coherence lengths — confirming theoretical predictions of cees dekker metallic conduct.
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes
All parameters were the identical for every panel With this online video, aside from the Original placement of the 6hb rod (shown in blue) to the nanopore. Simulations that terminated early due to translocation of the rod with the pore are marked by a grey track record.
Dynamic ParB–DNA interactions initiate and preserve a partition condensate for bacterial chromosome segregation
What if, in place of employing conventional top rated-down silicon electronics, transistors could possibly be crafted from the bottom up applying solitary natural and organic molecules since the switching features? This idea, which turned the basis of currently’s area of molecular electronics, initially emerged within the seventies.
Resolving the move sizing in condensin-pushed DNA loop extrusion identifies ATP binding given that the action-making course of action
[fourteen] In 2005 Dekker became involved with Netherlands-wide conversations about Clever Layout, a motion that he has because Plainly distanced himself from. Dekker advocates that science and faith usually are not in opposition but is usually harmonized.
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For example, we think about the nucleopore intricate, a gateway among the cell nucleus as well as cytoplasm. This is an extremely difficult system and as a consequence challenging to examine in a mobile, so we use biomimetics. We reconstruct holes then insert person features on the nucleopore complicated to check transport through it at The only-molecule level.’
Eventually, I'll briefly sketch several of our Thoughts to explore the developing of synthetic cells, specially our first measures to ascertain synthetic cell division.